PROTACs and Drug Synergism
Proteolysis-targeting chimeras (PROTACs) are redefining how medicines interact with disease-associated proteins. Rather than simply blocking a protein’s activity, these molecules…
10 October 2026 · 6 minute read
Insights
Published writing
Reviews of submitted inventions and standalone essays. Every article carries a verifiable publication record.
Who Owns the Invention?
An invention may begin with an individual’s insight, develop through artificial intelligence (AI), and eventually reach the market through a company. At each stage a different…
9 October 2026 · 5 minute read
Reading Nature’s Chemical Library with Machines
In 1967, malaria was killing soldiers and civilians across Southeast Asia, and the parasite Plasmodium falciparum had learned to survive chloroquine. China launched a secret…
2 October 2026 · 12 minute read
From Sequence Alignment to Generative Molecules
Bioinformatics, Computational Biology and AI in Drug Discovery
29 September 2026 · 6 minute read
Why AI Keeps Winning Discovery and Losing Phase III
Artificial intelligence has done something remarkable to the front end of drug discovery. Targets that once took years to nominate are now proposed in weeks. Molecules that once…
27 September 2026 · 7 minute read
Fatty acids as a design variable
The fatty acid has stopped being a passive greasy tail and become one of the most actively engineered parts of a modern drug. Across 2025 and 2026, three things happened at once…
26 September 2026 · 12 minute read
The Algorithm and the Clock
AI, Anti-Aging, and Protecting What AI Creates
17 September 2026 · 4 minute read
The Molecule Was Designed In Silico. The Biology Still Gets a Vote
Drug-like chemical space is usually estimated at around 10⁶⁰ molecules. The largest physical compound collections ever assembled hold a few million; DNA-encoded libraries reach…
8 September 2026 · 9 minute read
LESS BLANK-PAGE TIME AND MORE STRUCTURED INNOVATION
Innovation should be expensive to create, not unnecessarily expensive to protect
5 September 2026 · 6 minute read
MASTER AND ALGORITHM
"An algorithm has no master's liability of its own — the law still looks for the hand behind it."
3 September 2026 · 4 minute read
Artificial Intelligence in Drug Discovery: Scientific Translation, Patentability and AI-Enabled Patent Examination
AI in Drug Discovery: Where We Stand, and Whether You Can Patent It
2 September 2026 · Chemistry & Molecular Design · 7 minute read